Piceatannol,p56lck/Syk抑制剂 |中昊生物

Piceatannol

货号：P009-5MG | 规格：5MG | 价格：￥0.00 | 品牌：Arbor Assays

Arbor Assays Piceatannol/白皮杉醇,,CAS:10083-24-6,是SIRT1激活剂,p56lck/Syk抑制剂,抑制TNF诱导的NF-kB活化和基因表达。
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特性:
Activator of SIRT1
Inhibits NF-kB activation
Induces apoptosis
描述:
Activator of human deacetylase SIRT1. Anti-inflammatory, immunomodulatory and antiproliferative agent that inhibits p56lck and syk protein tyrosine kinases and inhibits TNF-induced NF-kB activation and gene expression. Piceatannol is a resveratrol analog formed by the cytochrome P450-catalyzed hydroxylation of resveratrol. Piceatannol exhibits potent anticancer properties by inducing apoptosis in BJAB Burkitt-like lymphoma cells with an ED50 value of 25 µM. Piceatannol also exhibits anti-proliferative and anti-inflammatory effects by inhibiting the activity of a wide range of tyrosine and serine/threonine protein kinases and suppressing NF-kB activation through inhibition of IkBa kinase.

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