Murine Anti-Factor IX抗体(GMA-184)
货号：GMA-184
|
规格：0.5 mg
|
价格：￥0.00
|
品牌：Greenmoab
Factor IX抗体,Murine Anti-Factor IX抗体(GMA-184)推荐用于ELISA和Immunoblotting应用。
Factor IX抗体
产品名称:
Murine Anti-Factor IX抗体
Clone GMA-184
描述:
Factor IX (FIX) is a vitamin K-dependent zymogen that plays an essential role in the coagulation cascade leading to thrombus formation. In the presence of calcium, activated Factor IX (FIXa) complexes with Factor VIIIa on phospholipid surfaces to create the tenase complex, which converts Factor X to its activated form. Absent or defective FIX is the cause of the X-linked recessive bleeding disorder hemophilia B. GMA-184 binds to FIX and FIXa in ELISA assays and detects FIX and the light chain of FIXa by Western blot.
物种反应性:
Human
来源:
Murine
特异性:
Light chain of FIXa
免疫原:
Human Factor IX
同型:
IgG2a
应用
ELISA:
Binds immobilized Human FIX/IXa.
Immunoblotting:
Western blot detects Human FIX and light chain of FIXa under reduced conditions.
Inhibition:
Does not prolong plasma clot time in APTT clotting assay.
BLI:
KD= 40 nM (kdis=8.3x10-3 sec-1) by bio-layer interferometry
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