Human Protein C Receptor, C-terminal 6x His tag
货号：HPCR-HIS
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规格：0.05 mg
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价格：￥0.00
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品牌：Molecular Innovations
Human Protein C Receptor, C-terminal 6x His tag是由北京中昊新生科技有限公司提供，Molecular Innovations专注于凝血和溶栓试剂，包括PAI-911、tPA、尿激酶、凝血因子、玻连蛋白、纤维蛋白原、纤连蛋白、肾素原/肾素、前激肽释放酶、激肽释放酶、白蛋白、纤溶酶原、纤溶酶、抗纤溶酶、凝血酶、抗凝血酶、补体成分和免疫球蛋白。
Endothelial Protein C Receptor (EPCR) is a type I transmembrane glycoprotein in the CD1/MHC family expressed in endothelial cells. Binding of Protein C to EPCR enhances activation by the thrombin-thrombomodulin complex. Bound APC cleaves Protease-Activated Receptor 1 (PAR1) leading to up-regulation of Protein C-induced genes. The glycosylated extracellular domain (Ser18-Ser210) is recombinantly produced in mammalian cell culture and purified then sterile filtered and lyophilized. Contains a 6X-Histidine tag at C terminus for purification. The protein purity is determined by SDS-PAGE. Add PBS to greater than 0.1 mg/ml, aliquot and freeze unused portion.
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