CDH1抗体

描述:Goat polyclonal to CDH1. CDH1 is a classical member of the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised consists of 5 cadherin repeats in the extracellular domain, one trans membrane domain, and a and a highly conserved intracellular domain that binds b-catenin and p120-catenin. CDH1 is involved in mechanisms regulating proliferation, mobility and cell-cell adhesions of epithelial cells. Loss of E-cadherin function or expression has been implicated in cancer metastasis and progression.

别名:ARC-1, CAM 120/80, CD324, CDH1, cdhc-A, CDHE, ECAD, E-Cad E-cadherin, Epithelial cadherin, l-cam, LCAM, P09803, P12830 / Q9R0T4, UVO, Uvomorulin, XBcad, XB-cadherin, XTCAD-1 antibody.

浓度: 3 mg/ml

抗体类型: 一抗.

Target Name: Anti-CDH1

Accession Number: ENSG00000039068

宿主: Goat

免疫原物种: Human

免疫原类型: Recombinant protein

免疫原: Purified Recombinant peptide derived from within residues 601 to 701 of human CDH1 produced in E. coli.

亚型: IgG

克隆: Polyclonal

已确认的反应种属: Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other

特异性: Detects endogenous levels of total E-cadherin protein by Western blot in the whole cell lysates (e.g. HeLa and COS-7). This Ab does not recognize CDH2.

储存缓冲液: PBS, 20% glycerol and 0.05% sodium azide

纯化: Epitope affinity purified

偶联物: Unconjugated

RRID: AB_2895341

经验证的应用: WB, IF, IHC-P, IHC-F

推荐稀释: WB:1:500-1:2,000, IF:1:50-1:200, IHC-P:1:200-1:1,000, IHC-F:1:200-1:1,000

储存条件: Store at -20 C for long-term storage. Store at 2-8 C for up to one month.



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