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JaICA氧化应激标志物选择指南
2023-05-10 9920 分享到:




DNA氧化标志物   DNA oxidation marker

标志物名称指标
应用备注
8-OHdG


New 8-OHdG Check ELISA Kit

(Code. KOG-200SE), ELISA:450nm, 96 wells

Assay range: 
0.5 -200 ng/mL

Urine,SerumSuitable for urine and animal serum. Assay time: 2.5 hours.(KOG-200SE)

Highly Sensitive 8-OHdG Check ELISA Kit
(Code. KOG-HS10E), ELISA: 450nm, 96 well

Assay range:

0.125-10 ng/mL

Urine,Serum,Cells

Suitable for human serum,tissue and cultured cells. Assay time: overnight +1.5 hours(KOG-HS10E)

Highly specific to 8-OHdG. Low cross reactivity to oxidized RNA(8-OHGua/8-OHG).

Anti 8-OHdG monoclonal antibody (N45.1)

(Code: MOG-020P / MOG-100P)

20 µg / 100 µgCells
Anti Thymidine Glycol (TG) antibody

(Code: MTG-100P) Clone 2E8

100 µg of IgGCellsDNA-specific oxidative stress marker. Specific to TG in DNA polymer.




脂质氧化标志物


HEL (13HPODE-Lys adduct)


Hexanoyl-Lysine (HEL) ELISA kit

(Code: KHL-700E), ELISA: 450nm, 96 wells

Assay range:2 - 700 nmol/LUrine,Serum,CellsNε-Hexanoyl-Lysine (HEL) is derived from 13-HPODE, and is a novel biomarker for early stage oxidation of n:6 polyunsaturated fatty acid. Detectable in urine, serum, tissue and cultured cells.

Anti Hexanoyl-Lysine (HEL) antibody

(Code: MHL-021P) Clone 5F12

20 µg of IgGCells

4-HNE

Anti 4-HNE monoclonal antibody (HNEJ2)

(Code: MHN-020P / MHN-100P)


20 µg /100 µg

Cells4-hydroxy-2-nonenal (4-HNE) is one of the major oxidized products of fatty acids. Specific to 4-HNE-modified proteins.

MDA

Anti MDA monoclonal antibody

(Code: MMD-030n) Clone 1F83

30 µg of IgGCells

Specific to Malondialdehyde(MDA)-protein adducts such as dihydropyridine-lysine (DHP-lysine).

By utilizing 3rd derivative analysis, more reliable results than that by traditional TBARS assay.

Malondialdehyde assay kit (TBARS)

(Code: KMD-008W) Colorimetric: 400-700nm scan

Assay range:
0.08 - 10 µmol/L

Urine,Serum,Cells
Anti Acrolein (ACR) antibody

(Code: MAR-020n / MAR-100n) Clone 5F6

20 µg /100 µgCellsSpecific to ACR modified proteins: formyl-dehydropiperidino-lysine (FDP-lysine).

Anti 4-hydroxy-2-hexenal (4-HHE) antibody

(Code: MHH-030n) Clone HHE53

30 µg of IgGCellsSpecific to HHE-histidine Michael adduct (HHE-His).

Anti Crotonaldehyde (CRA) antibody

(Code: MCA-030n) Clone 82D3

30 µg of IgGCellsSpecific to CRA-protein aduucts.

Anti Methylglyoxal (MG) antibody

(Code: MMG-030n) Clone 3C

30 µg of IgGCellsSpecific to MG-protein adduct (argpyrimidine).

Anti 7-ketocholesterol (7-KC) antibody

(Code: MKC-020n) Clone 35A

20 µg of IgGCellsBiomarker of cholesterol oxidation. Applicable for frozen tissue only.